FDA proposes excluding Novo, Lilly GLP-1s from compounding list

Finance  FDA proposes excluding Novo, Lilly GLP-1s from compounding list  The headquarters of the U.S. Food and Drug Administration in Silver Spring, Maryland, Nov. 4, 2009.  Jason Reed | Reuters  The ⁠Food and Drug ⁠Administration on Thursday proposed excluding the active ingredients in and s blockbuster obesity and diabetes medications from the ⁠list ⁠of drugs that outsourcing facilities can use for compounding in bulk.  If that proposal is finalized, the exclusion would likely limit the mass compounding — or the making of custom, often cheaper alternatives — of those medicines unless they appear on the FDAs ⁠drug shortage ⁠list. The agency said it will consider public comments, which can be submitted until late June, before making a final decision.  The FDA finds “no clinical need” for outsourcing facilities to compound them from bulk drug substances, the agency said in a release.  The proposal includes semaglutide, the active ingredient in Novo‘s obesity drug Wegovy and diabetes counterpart Ozempic, and tirzepatide, which is in Lilly’s weight loss injection Zepbound and diabetes shot Mounjaro. It also covers ⁠Novos older molecule liraglutide.  “When FDA-approved drugs are available, outsourcing facilities cannot lawfully compound ⁠using bulk drug substances unless there is a clear clinical ⁠need,” FDA Commissioner Marty Makary said in the release.  The agencys

04-30Industry

Cigna (CI) Stock Tumbles Despite Strong Q1 Earnings Beat and Raised Guidance

Q1 adjusted earnings per share reached $7.79, surpassing analyst expectations of $7.60Quarterly revenue increased 5% to $68.5 billion, exceeding the $66.3 billion forecastCompany elevated 2026 full-year EPS outlook to a minimum of $30.35, representing a $0.10 increaseShares declined approximately 3% despite positive results, with pharmacy benefits division cited as concernDavid Cordani stepping down as CEO on July 1; Brian Evanko, current COO, will assume leadership role  Cigna delivered an impressive first-quarter performance, yet investors responded with skepticism. The healthcare giant exceeded expectations on both the top and bottom lines and increased its annual forecast, but shares still tumbled in trading.  CIGNA $CI Q126 EARNINGS HIGHLIGHTS  Adj. Revenue: $68.52B (Est. $66.24B) ; +5% y/y  Adj. Operating EPS: $7.79 (Est. $7.61)  Healthcare Adj. Revenue: $11.48B (Est. $11.37B)  Healthcare Medical Care Ratio: 79.8% (Est. 81.0%)  FY Adj. Operating EPS Guide: At…  Adjusted earnings per share for the quarter totaled $7.79, representing growth from $6.74 in the prior-year period and surpassing the Streets $7.60 projection. Total revenue reached $68.5 billion, marking a 5% year-over-year climb and beating the anticipated $66.3 billion.  Management also revised upward its 2026 full-year EPS projection to at least $30.35, representing a $0.10 bump from the companys earlier guidance. This midpoint slightly exceeds the analyst consensus estimate of $30.33.  Cigna

04-30Industry

Conservative Forecasts Indicate Ozak AI Could Deliver Over 240× Returns Even Without Extreme Bull Market Conditions

ROI for Ozak AI is now estimated to be over 240x. This is based on conservative forecasts that exclude any bull market conditions. Simply put, sustaining the ongoing OZ presale momentum could roll out the said multiplier in the times to come. The closest estimated ROI is over 71x, possibly when public trading commences.  Conservative Forecasts for OZ  The current growth momentum of OZ is reflected in the 14x surge in the offer value. Ozak AI tokens have jumped from $0.001 to $0.014. It is also reflected in the accelerated accumulation of tokens by investors, who have so far bought more than 1 billion of the total supply.  It is estimated that sustaining this momentum could generate over 240x ROI for early investors. This translates to a token value of $3.36 – turning even a $50 holding into $12,000. Meaning, the token value could be more than the estimated mark, and the holding could turn into a bigger portfolio.  Meanwhile, 71x remains the closest anticipated ROI, possibly to be noted upon listing on exchanges for public trading. This comes to the $1 target price turning the same holding into $3,550.  Can Ozak AI Move Beyond 240x?  Ozak AI does have the potential to move beyond the

04-30Industry

Visa’s Ninth-Blockchain Expansion Redefines Global Settlements

On April 29, 2026, Visa announced that its stablecoin settlement pilot has officially reached a staggering $7 billion annual run rate.   This milestone coincides with the networks expansion to its ninth supported blockchain, further cementing the role of “stablecoin rails” as the backbone of modern commerce. What began as a cautious experiment with USDC on Ethereum and Solana has now blossomed into a multi-chain behemoth that allows global merchants to settle transactions with near-instant finality, bypassing the antiquated SWIFT and correspondent banking networks that governed the 20th century.  A historical artifact  The expansion is particularly significant because it marks the first time Visa has integrated “high-speed” Layer-2 environments alongside foundational Layer-1s to handle micro-transactions and high-frequency corporate settlements. By achieving a $7 billion run rate, Visa is proving that stablecoins are no longer just a “crypto-native” tool for trading but are a scalable solution for the $150 trillion global payments market.  This surge in volume is being driven by a new wave of “Tokenized Corporate Treasuries” — companies like Computershare and Securitize, who are now using these rails to move dividends and stock buybacks on-chain. As Visa bridges the gap between traditional bank accounts and digital ledgers, the “T+2” settlement window is effectively

04-30Industry

Nexo adds 0% credit lines for Solana and XRP holders

Nexo extends its 0% APR, no‑liquidation Zero-interest Credit to Solana and XRP, targeting holders who want dollar liquidity without selling their crypto.Nexo expands its Zero-interest Credit product to Solana‘s SOL and Ripple’s XRP, offering 0% APR loans with no liquidations.The move follows more than $170 million in zero-interest volume and a lending award at the 2026 FinTech Breakthrough Awards.The expansion arrives as DeFi TVL rebounds and crypto-backed lending gains traction across both crypto platforms and traditional finance.  Nexo is expanding its Zero-interest Credit product to include Solana‘s SOL and Ripple’s XRP as collateral, becoming the first major platform to offer 0% APR, no‑liquidation loans against either asset alongside its existing Bitcoin and Ethereum support.  The company is describing Zero-interest Credit (ZiC) as a fixed‑term borrowing product that lets users “borrow against your BTC (BTC), ETH (ETH), SOL (SOL), or XRP (XRP) at zero interest and zero fees,” with clients accessing dollar‑denominated liquidity without selling spot holdings or facing margin calls during the loan term.  Nexo opens 0% APR credit to SOL and XRP  ZiC has already generated more than $170 million in total loan volume with a 66% borrower renewal rate, and Nexo says over half of all ZiC proceeds remain on its platform,

04-30Industry

CLARITY Act Seen as XRP Breakout Catalyst by 65% of Institutions

Tech  CLARITY Act Seen as XRP Breakout Catalyst by 65% of Institutions  CLARITY Act Emerges as XRPs Potential Breakout Trigger  A clear shift in institutional crypto sentiment is bringing XRP back into focus, with regulatory clarity now seen as the key trigger for large-scale adoption.  Market analyst ChartNerd points to a Yahoo survey showing that consider the CLARITY Act a potential breakout catalyst for XRP, suggesting that policy certainty is starting to matter more than speculation in driving future demand.  For years, XRP has sat in a regulatory grey zone, with ongoing debate over whether it should be classified as a security or a commodity. This uncertainty has slowed deeper institutional participation, even as XRP has remained a steady reference point in cross-border payments and blockchain infrastructure conversations.  As a result, the CLARITY Act is increasingly seen as a potential turning point because it aims to establish clear legal boundaries for digital assets and settle long-running classification debates.  Having already been classified a digital commodity by the United States Security and Exchange Commisison (SEC), the Clarity Act could further ease compliance burdens for XRP and pave the way for deeper institutional participation.  CLARITY Act Momentum Builds as Institutions Eye XRP and Altcoins for Regulatory Breakout Shift  Earlier this month,

04-30Industry

CLARITY Act Seen as XRP Breakout Catalyst by 65% of Institutions

Tech  CLARITY Act Seen as XRP Breakout Catalyst by 65% of Institutions  A clear shift in institutional crypto sentiment is bringing XRP back into focus, with regulatory clarity now seen as the key trigger for large-scale adoption.  Market analyst ChartNerd points to a Yahoo survey showing that consider the CLARITY Act a potential breakout catalyst for XRP, suggesting that policy certainty is starting to matter more than speculation in driving future demand.  For years, XRP has sat in a regulatory grey zone, with ongoing debate over whether it should be classified as a security or a commodity. This uncertainty has slowed deeper institutional participation, even as XRP has remained a steady reference point in cross-border payments and blockchain infrastructure conversations.  As a result, the CLARITY Act is increasingly seen as a potential turning point because it aims to establish clear legal boundaries for digital assets and settle long-running classification debates.  Having already been classified a digital commodity by the United States Security and Exchange Commisison (SEC), the Clarity Act could further ease compliance burdens for XRP and pave the way for deeper institutional participation.  CLARITY Act Momentum Builds as Institutions Eye XRP and Altcoins for Regulatory Breakout Shift  Earlier this month, Bitrue noted that the CLARITY Act could

04-30Industry

The long con: How North Korean spies spent months in-person to drain $285 million from Drift

North Korean government-backed hackers are becoming more sophisticated, more precise and now account for more than 76% or nearly $600 million in crypto losses this year alone.  The $285 Drift Protocol exploit, for example, involved what TRMLabs describes as a long and “unprecedented in-person social engineering” attack. It included months of in-person meetings between North Korean proxies and Drift employees.  “North Korean proxies sitting across a table from protocol employees over a period of months. That is, to my knowledge, unprecedented in North Koreas crypto hacking campaign,” Ari Redbord, Global Head of Policy and Government Affairs at TRMLabs, told CoinDesk. “This is no longer just a remote keyboard operation.”  Ari‘s comments accompany TRMLabs’ new report released Thursday, which highlights how North Koreas two main hacking groups, DPRK and Lazarus, are responsible for 76% of all the crypto losses to hacks and exploits in 2026.  “What we are watching is not a North Korean campaign that is broader — it is one that is sharper,” Redbord said in the report. “North Korea is moving faster and more precisely than ever.”  “North Korea‘s cumulative crypto theft now exceeds $6 billion attributed incidents since 2017,” TRM Labs’ report adds.  TRMLabs‘ findings coincide with a Wasabi Protocol exploit using a

04-30Industry

SkyAI Price Prediction: SKYAI Surges Over 70% as Price Eyes $0.35 After Breakout

SkyAI breakout toward $0.30 shows strong demand but rising short-term exhaustion riskBullish structure remains intact with higher highs, yet key supports face pressureRising open interest signals growing leverage, increasing volatility and pullback risk  SkyAI (SKYAI) surged sharply this week, extending a powerful rally that pushed the token near its record highs. The asset now trades around $0.30 after a strong breakout, supported by rising volume and expanding participation.  Moreover, the latest move reflects growing speculative demand and renewed confidence among traders. With a 70.31% gain over the past seven days, SkyAI has entered a decisive phase where momentum remains strong, yet risks continue to build.  Bullish Structure Drives Momentum  The 4-hour chart shows a clear bullish structure with consistent higher highs and higher lows. Price recently broke out from consolidation and accelerated upward with strong conviction. Additionally, the move from $0.15 to $0.30 highlights aggressive buying pressure and sustained demand.  Key indicators support this trend. EMAs remain aligned in a bullish formation, confirming trend strength. Besides, the Supertrend indicator continues to signal a buy trend. Large bullish candles also suggest strong participation from high-volume traders.  SkyAI Price Dynamics (Source: Trading View)  Immediate resistance sits at the $0.30 psychological level. A confirmed break above this level could push

04-30Industry

Wasabi Protocol Hack: $4.55M Loss Rocks DeFi

The DeFi sector cannot escape the clutches of hack attacks; Ethereum and Base-based perpetuals trading platform Wasabi Protocol was robbed of $4.55 million on Thursday. Attackers seized the private key of the externally owned account (EOA) named wasabideployer.eth and immediately transferred the protocol‘s permission system’s single ADMIN_ROLE authority to themselves.  Wasabi Protocol Attack Technical Details  According to Blockaid‘s detection, the grantRole function was called and, using the UUPS standard, the perp vaults and Long Pool’s codes were replaced with malicious versions. Funds were quickly drained: wWETH, sUSDC, wBITCOIN, wPEPE vaults on Ethereum; sUSDC, wWETH, sBTC, sVIRTUAL, sAERO, and sBRETT vaults on Base were targeted. Users were advised to immediately revoke their LP token approvals.Hack Amount: 4.55 million dollarsTarget Chains: Ethereum and BaseWeak Point: Single ADMIN_ROLE deployer key  Drift Protocol Similarity and Latest News  The attack mechanics were identical to the $285 million loss of Solana-based DRIFT futures at the beginning of the month. North Korea-linked attackers had exploited the admin key without timelock or multisig protection in 12 minutes. Wasabi had a similar weakness: A single deployer key held all control. Breaking news: $DRIFT delisted from Upbit and Bithumb, trust erosion increasing post-hack.  ETH Price and DeFi Hack Impact  ETH is affected by the DeFi hack

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