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Eli Lilly weight loss drug retatrutide clears obesity trial

Finance　　Eli Lilly weight loss drug retatrutide clears obesity trial　　A sign with the company logo sits outside of the headquarters of Eli Lilly in Indianapolis, Indiana, on March 17, 2024.　　Scott Olson | Getty Images　　on Thursday said its next-generation drug cleared a crucial late-stage trial in patients with obesity, delivering significant weight loss across doses.　　The results bring Lilly one step closer to filing for approval of the weekly injection, called retatrutide, which works differently from existing shots and pills from both Lilly and Novo Nordisk. It also appears to be more effective than those options.　　The highest dose of retatrutide helped patients lose 28.3% of their weight — or 70.3 pounds — on average over 80 weeks, compared to 2.2% with placebo, when evaluating only patients who stayed on the drug.　　Roughly 45% of the 2,500 patients in the Phase 3 trial achieved 30% or more weight loss, Lilly said.　　The highest dose also helped patients with a BMI of 35 or above who participated in an extension of the study lose 30.3% of their weight on average over 104 weeks. That BMI threshold puts people at higher risk of cardiovascular complications or diabetes.　　While the drug appeared to show higher rates of certain gastrointestinal side

05-21

Hyperliquid (HYPE) adds $5 billion in value after explosive 50% rally

Finance　　Hyperliquid (HYPE) adds $5 billion in value after explosive 50% rally　　HYPE, the token of the decentralized blockchain and cryptocurrency exchange Hyperliquid, has been going against the wider digital assets grain in the last week of trading with a remarkable 49.62% rally to $58.47 – inches away from a new all-time high (ATH).　　Hyperliquid price one-week chart. Source: Finbold　　The move simultaneously added nearly $5 billion to HYPE token‘s market capitalization, which rose from $9.9 billion to $14.6 billion. Furthermore, Hyperliquid overtook Solana (SOL) in terms of fully diluted valuation (FDV), hitting $54.57 billion against SOL’s $54.22 billion, per the datashared on X on May 21.　　FDV represents the theoretical maximum market capitalization if all the possible tokens were in circulation.　　Meanwhile, the overall cryptocurrency market moved lower within the timeframe, erasing $130 billion as the total digital assets capitalization dropped from $2.68 trillion to $2.55 trillion.　　Total cryptocurrency market capitalization one-week chart. Source: TradingViewHow SpaceX IPO turned into Hyperliquid news that sent HYPE flying　　Elsewhere, by press time on May 21, it appears that Hyperliquid news that enabled the latest HYPE token rally was related to the highly anticipated SpaceX initial public offering (IPO).　　Specifically, launched pre-IPO perpetual futures (perps) for billionaire Elon Musks other most prominent

05-21

EU Commission Initiates Review of Crypto-Asset Regulation

The European Commission officially announced today, May 20, 2026, that it is seeking feedback on the current functioning of the European Unions crypto-asset framework.　　This initiative marks a pivotal moment in the evolution of the Markets in Crypto-Assets (MiCA) regulation, which has been the cornerstone of the EUs approach to digital assets.　　The Commissions decision to assess the framework stems from the rapid, ongoing evolution of digital asset markets since the initial drafting of MiCA.　　As global policy and technology continue to shift, regulators are eager to determine if the existing rules remain fit for purpose. This assessment process invites input from stakeholders, including industry participants, investors, and legal experts, to identify potential gaps in the current regime and evaluate how the EU should adapt to international developments in the sector.　　For the industry, this review is significant because it suggests a proactive approach toward “regulatory maintenance.” While MiCA provided much-needed clarity, the rise of new technologies, such as autonomous AI agents in DeFi and the tokenization of real-world assets, has introduced complexities that were less prominent when the original regulations were first conceived.　　By soliciting feedback now, the EU is signaling its intent to ensure that its regulatory landscape remains competitive while simultaneously addressing

05-21

BingX shows robust 66% growth YoY in CoinGecko perpetuals report

BingX recorded 565 new perpetual listings since 2025, averaging 35 new contracts monthly.The report identified BingX as having one of the strongest market share growth trajectories.BingX led in new listings of AI-related assets.　　BingX, a leading cryptocurrency exchange and Web3-AI company, today announced a partnership with CoinGecko for the release of the 2026 State of Crypto Perpetuals Report, an in-depth study examining the evolution of the perpetuals market across centralized and decentralized exchanges.　　The report identified accelerating growth in trading tied to tokenized real-world assets (RWAs), AI-linked markets, and multi-asset products, trends that closely align with BingXs leadership in multi-asset trading.　　Moreover, the report indicated that trading related to RWAs accelerated sharply in 2026, with first-quarter volumes already surpassing total 2025 levels.　　It also highlighted growing traction for stock perpetuals and other traditional finance-linked products as traders increasingly seek continuous access to diversified markets through crypto-native infrastructure.　　According to CoinGeckos 2026 State of Derivatives Report, BingX Experienced Strong Growth:#2 Perpetual Listings Globally: BingX recorded 565 new perpetual listings since 2025, averaging 35 new contracts monthly, and among the highest number of new listings of any exchange.Fastest Derivatives Growth Into 2026: The report identified BingX as having one of the strongest market share growth trajectories, increasing

05-21

Italy Traces €1 Million in Undeclared Bitcoin Ordinals Gains

Bitcoin　　Italy Traces €1 Million in Undeclared Bitcoin Ordinals Gains　　Italian financial investigators traced more than €1 million ($1.16 million) in undeclared crypto-related gains through a trading operation, Chainalysis said on May 20. The case centered on a suspect accused of concealing digital asset income while also unlawfully receiving public financial assistance. Authorities began reconstructing the activity after seizing a Ledger hardware wallet during a search operation.　　Investigators from the Economic and Financial Police Unit of Foggia, a division of Italy‘s Guardia di Finanza based in the southern Italian city of Foggia, worked alongside the Special Unit for Privacy Protection and Technological Fraud of Rome to examine transaction records tied to the wallet. The probe expanded after analysts identified repeated activity involving and BRC-20 assets. Chainalysis explained that modern hardware wallets generate multiple receiving addresses automatically, distributing transaction history across ’s Unspent Transaction Output model. Analysts grouped those addresses together through ownership heuristics, allowing investigators to isolate the wallet cluster responsible for the flows tied to the alleged tax violations.　　Chainalysis stressed:　　“No matter how sophisticated a scheme appears, the underlying technology leaves a permanent, immutable trail.”　　Ordinals technology allows individual satoshis to carry inscriptions directly on the . BRC-20 tokens use that structure to create

05-21

Institutions Add $4.6B to MSTR, Silvergate Exec Breaks SEC Silence, IG Taps Bitpanda

Tech　　Institutions Add $4.6B to MSTR, Silvergate Exec Breaks SEC Silence, IG Taps Bitpanda　　Strategy‘s MSTR stock attracted heavy institutional accumulation in the first quarter of 2026 even as shares dropped roughly 18%. Chief executive Phong Le disclosed Form 13F filings showing that 13 of the top 15 institutional shareholders increased their positions, lifting combined holdings by $4.6 billion, or 27%. Capital International led the wave with a $1.92 billion increase. Vanguard’s portfolio and capital management entities collectively added $967 million, while BlackRock Institutional Trust raised its stake by $377 million. Defiance ETFs entered the top 15 with a $511 million position. Only Morgan Stanley Investment Management trimmed exposure, shaving a modest $7 million during a steep Bitcoin drawdown.　　A closer look at the filings draws a sharp line between active conviction and passive index mechanics. Vanguard, BlackRock, State Street, and Geode Capital largely hold Strategy shares through index-tracking vehicles, meaning their additions partly reflect rebalancing rather than pure directional bets on Bitcoin exposure. By contrast, Capital International‘s nearly $2 billion increase represents a deliberate active wager, while Defiance ETFs’ fresh $511 million stake signals dedicated thematic demand. The split matters: passive flows wax and wane with index reconstitution, but active accumulation underscores

05-21

Why Bonds Have Been Wobbling Worldwide

Finance　　Why Bonds Have Been Wobbling Worldwide　　Bonds have been wobbling worldwide. The 30-year U.S. Treasury bond, now over 5%, is at its highest level since 2007. The British 30-year yield is surging to 6%. Japan spent years suppressing interest rates to virtually 0%. Now its 10-year is almost 2.8%, the 30-year, over 4%. Yields of German government obligations are rising as well.　　The immediate cause has been the fallout of the Iran war, but there‘s something far more fundamental at work. What has been happening in recent years is that governments have been weakening the value of their currencies. The most reliable metric for measuring that is gold. For a variety of reasons, the yellow metal has largely kept its intrinsic value for thousands of years. When you see gold prices change, what you’re actually witnessing is the changing values of currencies in which the gold price is denominated.　　The dollar price of gold per ounce was under $2,000 three years ago. Today its well over $4,000, even going over $5,000 a few months ago. Many other currencies are weaker than the dollar.　　What makes Japan particularly worrisome is that its huge national debt, which is proportionately more than twice that of the U.S.,

05-21

Binance Debuts SpaceX Pre-IPO Perp As Traders Expect $2 Trillion Valuation

Tech　　Binance Debuts SpaceX Pre-IPO Perp As Traders Expect $2 Trillion Valuation　　Binance has launched a new product that enables traders to make predictions about the price of private companies before they go public. The first “Pre-IPO Perpetual Contract” on the exchange is associated with the Elon Musks rocket and satellite company, SpaceX.　　Binance Futures Introduces SpaceX Pre-IPO Perpetual Contract　　The new perpetual contract of SPCXUSDT will be settled in Tether on Binance. It allows those who wish to trade with the anticipated market price of SpaceX before it goes public.　　Generally, such pre-IPO options are available to institutional entities and VCs. However, Binance aims to bring these offerings to retail crypto traders.　　Shunyet Jan, the Head of Spot and Derivatives Business at Binance, remarked on the launch. He said, “Pre-IPO perpetual futures is another example of how Binance is democratizing access to market opportunities by combining crypto-native infrastructure with major financial events. As interest in public listings continues to grow, were giving users a more flexible way to engage with anticipated IPOs earlier.”　　Moreover, he noted that the launch is part of Binances mission to become a “financial super app.” It will help to reach retail participants to investment opportunities that were not available before, he

05-21

SEC “Crypto Mom” Hester Peirce to Leave Agency in 2026

Crypto　　SEC “Crypto Mom” Hester Peirce to Leave Agency in 2026　　, one of the most well known people in US cryptocurrency regulation, is preparing to leave the Securities and Exchange Commission (SEC) after Regent University School of Law announced that she will join its faculty as an associate professor in November 2026.　　Regent University the appointment on May 19, with Dean S. Ernie Walton praising both Peirce and former government official Greg Jacob for their experience in law and public service. Walton described their decision to join the institution as a major benefit for students studying law, financial regulation, and public policy. Peirce is expected to teach subjects including securities regulation, financial markets, and digital assets.　　In the crypto industry, Peirce became very well known by the nickname “Crypto Mom” because of her repeated of the SECs approach toward digital asset companies. Since becoming an SEC commissioner in January of 2018, she consistently argued that regulators should encourage innovation instead of applying securities laws too broadly to emerging blockchain technologies.　　Her influence grew even more after she was appointed head of the SEC‘s in January of 2025. The task force was created during a major shift in the SEC’s stance toward cryptocurrency regulation and

05-21

Walmart (WMT) earnings Q1 2027

Finance　　Walmart (WMT) earnings Q1 2027　　issued a worse-than-expected financial outlook on Thursday as it reported fiscal first-quarter results, raising questions about the health of the U.S. consumer as high gas prices strain shopper budgets.　　The mega retailer stood by its fiscal 2027 outlook, which disappointed investors last quarter when it was issued. The retailer said its expecting adjusted earnings per share to be between $2.75 and $2.85, lower than expectations of $2.91, according to LSEG. Walmart said it anticipates net sales will rise between 3.5% and 4.5% for the year.　　Walmart also issued its outlook for its current quarter, which came in light of expectations, as well. It expects adjusted earnings per share will be between 72 cents and 74 cents, missing expectations of 75 cents. Walmart anticipates net sales will climb 4% to 5% for the quarter.　　Walmart‘s weaker-than-expected outlook comes as the largest U.S. retailer and its peers post relatively strong sales for the first quarter. The company’s revenue rose 7% in the first quarter, as the value player continues to see gains in its e-commerce business and with higher-income shoppers.　　So far this earnings season, other major companies have also said consumer spending has held up in the face of higher gas

05-21

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